WDR77 Antikörper (AA 292-342)
Kurzübersicht für WDR77 Antikörper (AA 292-342) (ABIN7454760)
Target
Alle WDR77 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
-
-
Bindungsspezifität
- AA 292-342
-
Verwendungszweck
- Rabbit anti-WDR77/MEP50 Antibody, Affinity Purified
-
Homologie
- Orangutan
-
Aufreinigung
- Affinity Purified
-
Immunogen
- between AA 292 and 342
-
Isotyp
- IgG
-
-
-
-
Applikationshinweise
-
IHC: 1:500 - 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
IP: 2 - 5 μg/mg lysate
WB: 1:2,000 - 1:10,000
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Konzentration
- 200 μg/mL
-
Buffer
- Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide
-
Konservierungsmittel
- Sodium azide
-
Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Lagerung
- 4 °C
-
Haltbarkeit
- 12 months
-
-
- WDR77 (WD Repeat Domain 77 (WDR77))
-
Andere Bezeichnung
- WDR77/MEP50
-
Hintergrund
- Background: WDR77/MEP50 is a component of the methylosome, a large protein arginine methyltransferase complex that modifies specific arginines to dimethylarginines in splicesomal Sm proteins. WDR77/MEP50 associates with the methyltransferase JBP1 (PRMT5) and is important for methylosome activity. WDR77/MEP50 has also been shown to associate with the polycomb group protein, SUZ12, and histone H2A. In this context, WDR77/MEP50 is proposed to function as an adaptor between PRMT5 and its substrate H2A to regulate transcription.
-
Gen-ID
- 79084
-
NCBI Accession
- NP_077007
-
UniProt
- Q9BQA1
-
Pathways
- Ribonucleoprotein Complex Subunit Organization
Target
-