WDR77 Antikörper

Produktnummer ABIN6241347

Produktdetails anti-WDR77 Antikörper

Target: WDR77 (WD Repeat Domain 77 (WDR77))

Reaktivität: Human, Maus

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser WDR77 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunocytochemistry (ICC)

Immunogen: Recombinant Protein

Anwendungsinformationen

Applikationshinweise: WB: 1:1000. ICC: 1:100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Lagerung: 4 °C,-20 °C

Details zu WDR77

Target: WDR77 (WD Repeat Domain 77 (WDR77))

Andere Bezeichnung: WDR77 (WDR77 Produkte)

Synonyme: MEP-50 antikoerper, MEP50 antikoerper, Nbla10071 antikoerper, RP11-552M11.3 antikoerper, p44 antikoerper, p44/Mep50 antikoerper, 2610003I18Rik antikoerper, 2610312E17Rik antikoerper, C79984 antikoerper, p44/MEP50 antikoerper, RGD1310479 antikoerper, mep50 antikoerper, valois antikoerper, WDR77 antikoerper, zgc:65780 antikoerper, zgc:77274 antikoerper, WD repeat domain 77 antikoerper, WD repeat domain 77 S homeolog antikoerper, WDR77 antikoerper, Wdr77 antikoerper, wdr77.S antikoerper, wdr77 antikoerper

Hintergrund: Non-catalytic component of the 20S PRMT5-containing methyltransferase complex, which modifies specific arginines to dimethylarginines in several spliceosomal Sm proteins and histones. This modification targets Sm proteins to the survival of motor neurons (SMN) complex for assembly into small nuclear ribonucleoprotein core particles. Might play a role in transcription regulation. The 20S PRMT5-containing methyltransferase complex also methylates the Piwi proteins (PIWIL1, PIWIL2 and PIWIL4), methylation of Piwi proteins being required for the interaction with Tudor domain-containing proteins and subsequent localization to the meiotic nuage.

UniProt: Q9BQA1

Pathways: Ribonucleoprotein Complex Subunit Organization