WDR77 Antikörper
Kurzübersicht für WDR77 Antikörper (ABIN6241347)
Target
Alle WDR77 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Immunogen
- Recombinant Protein
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Applikationshinweise
- WB: 1:1000. ICC: 1:100
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Lagerung
- 4 °C,-20 °C
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- WDR77 (WD Repeat Domain 77 (WDR77))
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Andere Bezeichnung
- WDR77
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Hintergrund
- Non-catalytic component of the 20S PRMT5-containing methyltransferase complex, which modifies specific arginines to dimethylarginines in several spliceosomal Sm proteins and histones. This modification targets Sm proteins to the survival of motor neurons (SMN) complex for assembly into small nuclear ribonucleoprotein core particles. Might play a role in transcription regulation. The 20S PRMT5-containing methyltransferase complex also methylates the Piwi proteins (PIWIL1, PIWIL2 and PIWIL4), methylation of Piwi proteins being required for the interaction with Tudor domain-containing proteins and subsequent localization to the meiotic nuage.
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UniProt
- Q9BQA1
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Pathways
- Ribonucleoprotein Complex Subunit Organization
Target
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