WRNIP1 Antikörper (AA 400-450)
Kurzübersicht für WRNIP1 Antikörper (AA 400-450) (ABIN7454746)
Target
Alle WRNIP1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 400-450
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Verwendungszweck
- Rabbit anti-WRNIP1 Antibody, Affinity Purified
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Homologie
- Mouse,Rat
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Aufreinigung
- Affinity Purified
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Immunogen
- between AA 400 and 450
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Isotyp
- IgG
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Applikationshinweise
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IHC: 1:500 - 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
IP: 2 - 10 μg/mg lysate
WB: 1:1,000 - 1:5,000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 1000 μg/mL
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Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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Haltbarkeit
- 12 months
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- WRNIP1 (Werner Helicase Interacting Protein 1 (WRNIP1))
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Andere Bezeichnung
- WRNIP1
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Hintergrund
- Background: WRNIP1 (Werner helicase interacting protein 1) was identified as a protein that interacts with the N-terminal region of Werner protein (WRN). WRN is a RecQ DNA helicase important to DNA repair and is the causative gene of Werner syndrome (WS), an autosomal recessive disease characterized by premature aging. WRNIP1 has been shown to interact with DNA polymerase delta (pol delta) and play a role in pol delta-mediated DNA synthesis. Additionally, WRNIP1 has been shown to interact with polyubiquitin chains indicating a link between ubiquitination and the DNA repair pathway.
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Gen-ID
- 56897
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NCBI Accession
- NP_064520
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UniProt
- Q96S55
Target
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