PALB2 Antikörper (AA 675-725)
Kurzübersicht für PALB2 Antikörper (AA 675-725) (ABIN7454733)
Target
Alle PALB2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
-
-
Bindungsspezifität
- AA 675-725
-
Verwendungszweck
- Rabbit anti-PALB2 Antibody, Affinity Purified
-
Aufreinigung
- Affinity Purified
-
Immunogen
- between AA 675 and 725
-
Isotyp
- IgG
-
-
-
-
Applikationshinweise
-
IHC: 1:500 - 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
IP: 2 - 10 μg/mg lysate
WB: 1:2,000 - 1:10,000
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Konzentration
- 1000 μg/mL
-
Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
-
Konservierungsmittel
- Sodium azide
-
Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Lagerung
- 4 °C
-
Haltbarkeit
- 12 months
-
-
- PALB2 (Partner and Localizer of BRCA2 (PALB2))
-
Andere Bezeichnung
- PALB2
-
Hintergrund
- Background: PALB2 (partner and localizer of BRCA2) interacts with BRCA2 and promotes BRCA2 localization and stability. PALB2 is also known as FANCN. Bi-allelic mutations in PALB2 result in Fanconi anemia disorder and breast cancer susceptibility. At the cellular level, PALB2 is important to the DNA damage response and chromosome stability and is essential to BRCA2 function.
-
Gen-ID
- 79728
-
NCBI Accession
- NP_078951
-
UniProt
- Q86YC2
-
Pathways
- DNA Reparatur
Target
-