RPA2 Antikörper (AA 220-270)
Kurzübersicht für RPA2 Antikörper (AA 220-270) (ABIN7454567)
Target
Alle RPA2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 220-270
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Verwendungszweck
- Goat anti-RPA32 Antibody, Affinity Purified
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Homologie
- Mouse,Rat,Orangutan
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Aufreinigung
- Affinity Purified
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Immunogen
- Between AA 220 and 270
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Isotyp
- IgG
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Applikationshinweise
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IHC: 1:500 - 1:2,000. Epitope retrieval with citrate buffer pH 6.0 or Tris-EDTA pH 9.0 is recommended for FFPE tissue sections.
IP: Not recommended
WB: 1:500 - 1:2,500
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 1000 μg/mL
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Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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Haltbarkeit
- 12 months
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- RPA2 (Replication Protein A2, 32kDa (RPA2))
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Andere Bezeichnung
- RPA32
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Hintergrund
- Background: Replication protein A (RPA) is a multisubunit complex that carries out DNA mismatch repair (MMR) in association with MSH2 (a subunit of human MutS heterodimers), MLH1 (a subunit of human MutL heterodimers), PCNA, and DNA polymerase-delta. RPA is composed of a heterotrimer that includes subunits of 70 kDa (RPA1), 32 kDa (RPA2), and 14 kDa (RPA3). RPA2, the 32 kDa subunit, is phosphorylated by the cdc2 family of kinases when cells enter S-phase and in response to DNA damage by ATM, ATR, and DNA-PK.
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Gen-ID
- 6118
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NCBI Accession
- NP_002937
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UniProt
- P15927
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Pathways
- Telomere Maintenance, DNA Reparatur, Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA
Target
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