Cullin 4B Antikörper (AA 863-913)
Kurzübersicht für Cullin 4B Antikörper (AA 863-913) (ABIN7454566)
Target
Alle Cullin 4B (CUL4B) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
 - AA 863-913
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Verwendungszweck
 - Rabbit anti-Cul4B Antibody, Affinity Purified
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Aufreinigung
 - Affinity Purified
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Immunogen
 - Between AA 863 and 913
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Isotyp
 - IgG
 
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Applikationshinweise
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IHC: 1:500 - 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
IP: Not recommended
WB: 1:2,000 - 1:10,000
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Beschränkungen
 - Nur für Forschungszwecke einsetzbar
 
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Konzentration
 - 1000 μg/mL
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Buffer
 - Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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Konservierungsmittel
 - Sodium azide
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Vorsichtsmaßnahmen
 - This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
 - 4 °C
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Haltbarkeit
 - 12 months
 
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- Cullin 4B (CUL4B)
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Andere Bezeichnung
 - Cul4B
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Hintergrund
 - Background: Cullin-4B is a member of the cullin family. Cullin-4B forms a complex that functions as an E3 ubiquitin ligase and catalyzes the polyubiquitination of specific protein substrates in the cell. Cullin-4B interacts with a ring finger protein, and is required for the proteolysis of several regulators of DNA replication including chromatin licensing and DNA replication factor 1 and cyclin E [taken from NCBI Entrez Gene (Gene ID: 8450)].
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Gen-ID
 - 8450
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NCBI Accession
 - NP_003579
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UniProt
 - Q13620
 
Target
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