Filamin A Antikörper (AA 400-450)

Produktnummer ABIN7454529

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch Filamin A in WB und IHC (fp). Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für Filamin A Antikörper (AA 400-450) (ABIN7454529)

Target: Filamin A (FLNA) (Filamin A, alpha (FLNA))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Filamin A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Produktdetails anti-Filamin A Antikörper

Bindungsspezifität: AA 400-450

Verwendungszweck: Rabbit anti-Filamin A Antibody, Affinity Purified

Aufreinigung: Affinity Purified

Immunogen: between AA 400 and 450

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

IHC: 1:500 - 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: Not recommended. Use rabbit anti-Filamin A antibody A301-134A or A301-135A.

WB: 1:2,000 - 1:10,000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 200 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Haltbarkeit: 12 months

Details zu Filamin A

Target: Filamin A (FLNA) (Filamin A, alpha (FLNA))

Andere Bezeichnung: Filamin A

Hintergrund: Background: Filamin A is an actin-binding protein that crosslinks and promotes orthogonal branching of actin filaments and also functions to anchor transmembrane proteins and intracellular signaling proteins to the actin cytoskeleton. As a scaffolding protein, filamin A is able to act as a link between cell membrane receptors and intracellular signaling proteins. Defects in filamin A are associated with multiple human diseases characterized by abnormalities in bone and neurological development.

Gen-ID: 2316

NCBI Accession: NP_001447

UniProt: P21333

Pathways: T-Zell Rezeptor Signalweg, Maintenance of Protein Location