Caldesmon Antikörper (AA 675-725)
Kurzübersicht für Caldesmon Antikörper (AA 675-725) (ABIN7454504)
Target
Alle Caldesmon (CALD1) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 675-725
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Verwendungszweck
- Rabbit anti-Caldesmon Antibody, Affinity Purified
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Homologie
- Rat,Chicken,Turkey
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Aufreinigung
- Affinity Purified
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Immunogen
- Between AA 675 and 725
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Isotyp
- IgG
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Applikationshinweise
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IHC: 1:500 - 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
IP: 2 - 10 μg/mg lysate
WB: Not recommended. Use rabbit anti-Caldesmon antibody A304-165A.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 1000 μg/mL
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Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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Haltbarkeit
- 12 months
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- Caldesmon (CALD1) (Caldesmon 1 (CALD1))
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Andere Bezeichnung
- Caldesmon
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Hintergrund
- Background: Caldesmon is a calmodulin- and actin-binding protein that plays an essential role in the regulation of smooth muscle and nonmuscle contraction. The conserved domain of caldesmon possesses the binding activities to Ca(2+)-calmodulin, actin, tropomyosin, myosin, and phospholipids. This protein is a potent inhibitor of the actin-tropomyosin activated myosin MgATPase, and serves as a mediating factor for Ca(2+)-dependent inhibition of smooth muscle contraction [taken from NCBI Entrez Gene (Gene ID: 800)].
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Gen-ID
- 800
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NCBI Accession
- NP_149129
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UniProt
- Q05682
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Pathways
- Myometrial Relaxation and Contraction
Target
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