TIGAR Antikörper (AA 220-270)
Kurzübersicht für TIGAR Antikörper (AA 220-270) (ABIN7454443)
Target
Alle TIGAR Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
-
-
Bindungsspezifität
- AA 220-270
-
Verwendungszweck
- Rabbit anti-TIGAR Antibody, Affinity Purified
-
Aufreinigung
- Affinity Purified
-
Immunogen
- between AA 220 and 270
-
Isotyp
- IgG
-
-
-
-
Applikationshinweise
-
IHC: 1:500 - 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
IP: 10 μg/mg lysate
WB: Not recommended. Use rabbit anti-TIGAR antibody A302-285A.
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Konzentration
- 1000 μg/mL
-
Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
-
Konservierungsmittel
- Sodium azide
-
Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Lagerung
- 4 °C
-
Haltbarkeit
- 12 months
-
-
- TIGAR (TP53 induced glycolysis regulatory phosphatase (TIGAR))
-
Andere Bezeichnung
- TIGAR
-
Hintergrund
- Background: TIGAR (TP53-induced glycolysis and apoptosis regulator) is a protein with sequence similarity to the bisphosphate domain of the glycolytic enzyme that degrades fructose-2,6-bisphosphate. The protein functions by blocking glycolysis and directing the pathway into the pentose phosphate shunt. Expression of this protein also protects cells from DNA damaging reactive oxygen species and provides some protection from DNA damage-induced apoptosis [taken from NCBI GeneID:57103].
-
Gen-ID
- 57103
-
NCBI Accession
- NP_065108
-
UniProt
- Q9NQ88
-
Pathways
- Warburg Effekt
Target
-