BTBD12 Antikörper (AA 1784-1834)

Produktnummer ABIN7454441

Dieses Anti-BTBD12-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von BTBD12 in IP und IHC (fp). Geeignet für Human.

Kurzübersicht für BTBD12 Antikörper (AA 1784-1834) (ABIN7454441)

Target: BTBD12 (BTB (POZ) Domain Containing 12 (BTBD12))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser BTBD12 Antikörper ist unkonjugiert

Applikation: Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Produktdetails anti-BTBD12 Antikörper

Bindungsspezifität: AA 1784-1834

Verwendungszweck: Rabbit anti-BTBD12 Antibody, Affinity Purified

Aufreinigung: Affinity Purified

Immunogen: between AA 1784 and 1834

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

IHC: 1:500 - 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 10 μg/mg lysate

WB: Not recommended. A302-270A has not performed satisfactorily when used for WB of BTBD12 in crude preparations (e.g. whole cell lysate). This antibody can be used for WB of enriched (e.g. immunoprecipitated) sources of BTBD12.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Haltbarkeit: 12 months

Details zu BTBD12

Target: BTBD12 (BTB (POZ) Domain Containing 12 (BTBD12))

Andere Bezeichnung: BTBD12

Hintergrund: Background: BTBD12 (BTBD12 domain-containing protein 12) has been identified as the human ortholog of the yeast Slx4p and drosophila MUS312 DNA repair factors. BTBD12 is an ATM/ATR checkpoint substrate that functions as part of a Holliday junction resolvase and is important for DNA interstrand crosslink repair.

Gen-ID: 84464

NCBI Accession: NP_115820

UniProt: Q8IY92

Pathways: DNA Reparatur