PELP1 Antikörper (AA 25-75)

Produktnummer ABIN7454378

Der Kaninchen Polyklonal anti-PELP1 Antikörper (ABIN7454378) detektiert spezifisch PELP1 in IP und IHC (fp). Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für PELP1 Antikörper (AA 25-75) (ABIN7454378)

Target: PELP1 (Proline-, Glutamic Acid- and Leucine-Rich Protein 1 (PELP1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PELP1 Antikörper ist unkonjugiert

Applikation: Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Produktdetails anti-PELP1 Antikörper

Bindungsspezifität: AA 25-75

Verwendungszweck: Rabbit anti-PELP1/MNAR Antibody, Affinity Purified

Homologie: Monkey

Aufreinigung: Affinity Purified

Immunogen: between AA 25 and 75

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

IHC: 1:500 - 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 2 - 5 μg/mg lysate

WB: Not recommended. Use rabbit anti-PELP1/MNAR antibody A300-180A.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Haltbarkeit: 12 months

Details zu PELP1

Target: PELP1 (Proline-, Glutamic Acid- and Leucine-Rich Protein 1 (PELP1))

Andere Bezeichnung: PELP1/MNAR

Hintergrund: Background: PELP1/MNAR was identified as an SH2 domain interacting protein that interacts with Lck, c-Src, and other members of the Src kinase family. PELP1/MNAR appears to function as a general coregulator and interacts with multiple nuclear receptors and transcription factors. PELP1/MNAR has also been shown to participate in nongenomic signaling via an association with a multiprotein complex, the ""signalsome"" involving ERalpha, Src kinase, PI3K, SHC, and G-proteins. As a transcriptional coregulator and signaling protein, PELP/MNAR mediates a variety of cellular functions such as cell proliferation, apoptosis, differentiation, oncogenesis and metastasis.

Gen-ID: 27043

UniProt: Q8IZL8