KDM4A Antikörper (AA 350-400)
Kurzübersicht für KDM4A Antikörper (AA 350-400) (ABIN7454377)
Target
Alle KDM4A Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
-
-
Bindungsspezifität
- AA 350-400
-
Verwendungszweck
- Rabbit anti-JMJD2A Antibody, Affinity Purified
-
Homologie
- Orangutan
-
Aufreinigung
- Affinity Purified
-
Immunogen
- between AA 350 and 400
-
Isotyp
- IgG
-
-
-
-
Applikationshinweise
-
IHC: 1:500 - 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
IP: 2 - 5 μg/mg lysate
WB: Not recommended. Use rabbit anti-JMJD2A antibody A300-861A.
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Konzentration
- 1000 μg/mL
-
Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
-
Konservierungsmittel
- Sodium azide
-
Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Lagerung
- 4 °C
-
Haltbarkeit
- 12 months
-
-
- KDM4A (Lysine (K)-Specific Demethylase 4A (KDM4A))
-
Andere Bezeichnung
- JMJD2A
-
Hintergrund
- Background: JMJD2A is a member of the jumonji (jmj) domain containing gene family of histone demethylases that plays a role in chromatin regulation and influences transcriptional activation and suppression. Some recently characterized members of the jmj family include JARID1A/RBP2, JARID1C, JMJD1A, JMJD1B, JMJD1C, JMJD2A, JMJD2C and JMJD2D. JMJD2A is a trimethylation-specific demethylase and functions as a transcriptional repressor. JMJD2A interacts with pRb and class one histone deacetylases to mediate repression of E2F-regulated promoters.
-
Gen-ID
- 9682
-
NCBI Accession
- NP_055478
-
UniProt
- O75164
-
Pathways
- Warburg Effekt
Target
-