SYK Antikörper (AA 250-300)
Kurzübersicht für SYK Antikörper (AA 250-300) (ABIN7454368)
Target
Alle SYK Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 250-300
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Verwendungszweck
- Rabbit anti-SYK Antibody, Affinity Purified
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Aufreinigung
- Affinity Purified
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Immunogen
- between AA 250 and 300
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Isotyp
- IgG
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anti-Spleen tyrosine Kinase (SYK) (AA 5-360) antibody
SYK Reaktivität: Human, Maus, Ratte WB, IP, IHC (p), ICC Wirt: Maus Monoclonal SYK-01 unconjugated
anti-Spleen tyrosine Kinase (SYK) (Internal Region) antibodySYK Reaktivität: Human, Maus, Ratte WB, IF, IP, IHC (p), ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Spleen tyrosine Kinase (SYK) (pTyr525) antibodySYK Reaktivität: Human, Maus, Ratte, Affe WB, IHC, ELISA, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Spleen tyrosine Kinase (SYK) (pTyr348) antibodySYK Reaktivität: Human, Maus, Ratte, Affe WB, IHC, ELISA, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Spleen tyrosine Kinase (SYK) (pTyr323) antibodySYK Reaktivität: Human, Maus, Ratte, Affe WB, IHC, ELISA, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Spleen tyrosine Kinase (SYK) (AA 217-356) antibodySYK Reaktivität: Human ELISA, ICC, FACS Wirt: Maus Monoclonal 2G11E6 unconjugated
anti-Spleen tyrosine Kinase (SYK) (AA 217-356) antibodySYK Reaktivität: Human WB, ELISA, FACS Wirt: Maus Monoclonal 3D1G10 unconjugated
anti-Spleen tyrosine Kinase (SYK) (AA 387-417), (C-Term) antibodySYK Reaktivität: Human, Maus WB, IHC (p) Wirt: Kaninchen Polyclonal RB03097 unconjugated
anti-Spleen tyrosine Kinase (SYK) (AA 374-635) antibodySYK Reaktivität: Human WB, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Spleen tyrosine Kinase (SYK) (pTyr525), (pTyr526) antibodySYK Reaktivität: Human, Maus WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
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Applikationshinweise
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IHC: 1:500 - 1:2,000. Epitope retrieval with Tris-EDTA pH 9.0 is recommended for FFPE tissue sections.
IP: 1 - 4 μg/mg lysate
WB: Not recommended. Use rabbit anti-SYK antibody A300-559A.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 1000 μg/mL
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Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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Haltbarkeit
- 12 months
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- SYK (Spleen tyrosine Kinase (SYK))
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Andere Bezeichnung
- SYK
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Hintergrund
- Background: SYK (spleen tyrosine kinase) is a ubiquitously expressed tyrosine kinase that functions in mediating B and T-cell receptor signaling and is also important to various aspects of leukocyte function that involve cytoskeleton remodeling. In mediating hematopoietic cell signaling, SYK is a substrate of src family kinase activity and is a key-regulator of Akt kinase activity. SYK has also been found to be highly expressed in the mammary gland and has been shown to inhibit tumor growth and metastasis. Invasive breast tumor cell lines have been shown to exhibit reduced or absent levels of SYK, further implicating a role in tumorigenesis and metastasis.
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Gen-ID
- 6850
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NCBI Accession
- NP_003168
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UniProt
- P43405
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Pathways
- Fc-epsilon Rezeptor Signalübertragung, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Thromboxane A2 Receptor Signaling, BCR Signaling
Target
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