Rekombinanter Liver Arginase Antikörper (AA 1-322)

Produktnummer ABIN7454020

Der Kaninchen Monoklonal Anti-Liver Arginase-Antikörper wurde für WB, IHC, IP, ICC und IF (p) validiert. Er ist geeignet, Liver Arginase in Proben von Human zu detektieren.

Kurzübersicht für Rekombinanter Liver Arginase Antikörper (AA 1-322) (ABIN7454020)

Target: Liver Arginase (ARG1) (Arginase, Liver (ARG1))

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser Liver Arginase Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunocytochemistry (ICC), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Klon: BLR036F

Produktdetails anti-Liver Arginase Antikörper

Bindungsspezifität: AA 1-322

Verwendungszweck: Rabbit anti-Arginase 1 Recombinant Monoclonal Antibody [BLR036F]

Immunogen: residues 1-322 (FL)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1000 μg/mL

Buffer: Borate Buffered Saline (BBS) pH 8.2 with 0.09 % Sodium Azide, BSA-Free

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Haltbarkeit: 12 months

Details zu Liver Arginase

Target: Liver Arginase (ARG1) (Arginase, Liver (ARG1))

Andere Bezeichnung: Arginase 1

Hintergrund: Background: Arginase1 is a key element of the urea cycle converting L-arginine to urea and L-ornithine, which is further metabolized into metabolites proline and polyamides that drive collagen synthesis and bioenergetic pathways critical for cell proliferation, respectively, the urea cycle takes place primarily in the liver and, to a lesser extent, in the kidneys. Arginase catalyzes the hydrolysis of arginine to ornithine and urea. At least two isoforms of mammalian arginase exist (types I and II) which differ in their tissue distribution, subcellular localization, immunologic crossreactivity and physiologic function. The type I isoform encoded by this gene, is a cytosolic enzyme and expressed predominantly in the liver as a component of the urea cycle. Inherited deficiency of this enzyme results in argininemia, an autosomal recessive disorder characterized by hyperammonemia.  [taken from the Universal Protein Resource (UniProt) P05089].

Gen-ID: 383

NCBI Accession: NP_001231367

UniProt: P05089

Pathways: Cellular Response to Molecule of Bacterial Origin