Rekombinanter Cadherin 5 Antikörper (AA 25-595)
Kurzübersicht für Rekombinanter Cadherin 5 Antikörper (AA 25-595) (ABIN7453992)
Target
Alle Cadherin 5 (CDH5) Antikörper anzeigenAntikörpertyp
Reaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 25-595
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Verwendungszweck
- Rabbit anti-VE-Cadherin Recombinant Monoclonal Antibody [BLR239K]
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Immunogen
- residues 25-595 (ECD)
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Isotyp
- IgG
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 1000 μg/mL
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Buffer
- Borate Buffered Saline (BBS) pH 8.2 with 0.09 % Sodium Azide, BSA-Free
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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Haltbarkeit
- 12 months
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- Cadherin 5 (CDH5)
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Andere Bezeichnung
- VE-Cadherin
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Hintergrund
- Background: Cadherins are calcium-dependent cell adhesion proteins that preferentially interact with themselves in a homophilic manner in adjacent cells. VE-Cadherin, or Cadherin-5 plays an important role in endothelial cell biology through control of the cohesion and organization of the intercellular junctions. It associates with alpha-catenin forming a link to the cytoskeleton and acts in concert with KRIT1 and MPP5 to establish and maintain correct endothelial cell polarity and vascular lumen. [taken from the Universal Protein Resource (UniProt) P33151].
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Gen-ID
- 12562
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NCBI Accession
- NP_033998
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UniProt
- P55284
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Pathways
- Cell-Cell Junction Organization, Signaling Events mediated by VEGFR1 and VEGFR2
Target
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