Rekombinanter ThPok (AA 250-300) Antikörper

Produktnummer ABIN7453988

Der Kaninchen Monoklonal anti-ThPok Antikörper (Klon BLR191J) (ABIN7453988) detektiert spezifisch ThPok in IP, WB, FACS, ICC und IHC. Dieser Antikörper reagiert spezifisch mit Proben aus Human und Maus.

Kurzübersicht für Rekombinanter ThPok (AA 250-300) Antikörper (ABIN7453988)

Target: ThPok

Antikörpertyp: Recombinant Antibody

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Unkonjugiert

Applikation: Immunoprecipitation (IP), Western Blotting (WB), Flow Cytometry (FACS), Immunocytochemistry (ICC), Immunohistochemistry (IHC)

Klon: BLR191J

Produktdetails

Bindungsspezifität: AA 250-300

Verwendungszweck: Rabbit anti-ThPOK Recombinant Monoclonal Antibody [BLR191J] - BSA-Free

Aufreinigung: Purified

Immunogen: between AA 250 and 300

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1000 μg/mL

Buffer: Borate Buffered Saline (BBS) pH 8.2 with 0.09 % Sodium Azide, BSA-Free

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: 2 - 8 °C

Haltbarkeit: 12 months

Antigendetails

Target: ThPok

Hintergrund: ZBTB7B is a transcription factor that acts as a key regulator of lineage commitment of immature T-cell precursors. ZBTB7B is necessary and sufficient for commitment of CD4 lineage, while its absence causes CD8 commitment. Development of immature T-cell precursors (thymocytes) to either the CD4 helper or CD8 killer T-cell lineages correlates precisely with their T-cell receptor specificity for major histocompatibility complex class II or class I molecules, respectively. ZBTB7B is also a transcriptional repressor of the collagen COL1A1 and COL1A2 genes and may also function as a repressor of fibronectin and possibly other extracellular matrix genes [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/ O15156].

Gen-ID: 51043

UniProt: O15156