This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
4 °C
Haltbarkeit
12 months
Target
FAP
(Fibroblast Activation Protein, alpha (FAP))
Andere Bezeichnung
Fibroblast Activation Protein alpha/FAP
Hintergrund
Background: Fibroblast Activation Protein alpha, or FAP, is a homodimeric integral membrane gelatinase belonging to the serine protease family. It is selectively expressed in reactive stromal fibroblasts of epithelial cancers, granulation tissue of healing wounds, and malignant cells of bone and soft tissue sarcomas. FAP is involved in the control of fibroblast growth or epithelial-mesenchymal interactions during development, tissue repair, and epithelial carcinogenesis. [taken from NCBI Entrez Gene (Gene ID: 2191)].