Rekombinanter Liver Arginase Antikörper (AA 1-322)

Produktnummer ABIN7453894

Dieses Kaninchen Monoklonal-Antikörper erkennt spezifisch Liver Arginase in WB, IHC (fp) und IP. Er zeigt eine Reaktivität gegenüber Maus.

Kurzübersicht für Rekombinanter Liver Arginase Antikörper (AA 1-322) (ABIN7453894)

Target: Liver Arginase (ARG1) (Arginase, Liver (ARG1))

Antikörpertyp: Recombinant Antibody

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser Liver Arginase Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp)), Immunoprecipitation (IP)

Klon: BLR161J

Produktdetails anti-Liver Arginase Antikörper

Bindungsspezifität: AA 1-322

Verwendungszweck: Rabbit anti-Arginase 1 Recombinant Monoclonal Antibody [BLR161J]

Immunogen: residues 1-322 (FL)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

IHC: 1:100 to 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 20 μL/1 mg lysate

WB: 01:01,00

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 100 μg/mL

Buffer: Borate Buffered Saline (BBS) pH 8.2 with 0.1 % BSA and 0.09 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Haltbarkeit: 12 months

Details zu Liver Arginase

Target: Liver Arginase (ARG1) (Arginase, Liver (ARG1))

Andere Bezeichnung: Arginase 1

Hintergrund: Background: Arginase1 is a key element of the urea cycle converting L-arginine to urea and L-ornithine, which is further metabolized into metabolites proline and polyamides that drive collagen synthesis and bioenergetic pathways critical for cell proliferation, respectively, the urea cycle takes place primarily in the liver and, to a lesser extent, in the kidneys. Arginase catalyzes the hydrolysis of arginine to ornithine and urea. At least two isoforms of mammalian arginase exist (types I and II) which differ in their tissue distribution, subcellular localization, immunologic crossreactivity and physiologic function. The type I isoform encoded by this gene, is a cytosolic enzyme and expressed predominantly in the liver as a component of the urea cycle. Inherited deficiency of this enzyme results in argininemia, an autosomal recessive disorder characterized by hyperammonemia.  [taken from the Universal Protein Resource (UniProt) P05089].

Gen-ID: 11846

NCBI Accession: NP_031508

UniProt: Q61176

Pathways: Cellular Response to Molecule of Bacterial Origin