TOP2B Antikörper (AA 1475-1525)
Kurzübersicht für TOP2B Antikörper (AA 1475-1525) (ABIN7453888)
Target
Alle TOP2B Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 1475-1525
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Verwendungszweck
- Rabbit anti-Topo II Beta Antibody, Affinity Purified
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Aufreinigung
- Affinity Purified
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Immunogen
- between AA 1475 and 1525
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Isotyp
- IgG
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Applikationshinweise
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IHC: 1:100 to 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
IP: 2 - 10 μg/mg lysate
WB: 1:2,000 - 1:10,000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 200 μg/mL
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Buffer
- Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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Haltbarkeit
- 12 months
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- TOP2B (Topoisomerase (DNA) II beta 180kDa (TOP2B))
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Andere Bezeichnung
- Topo II Beta
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Hintergrund
- Background: Topoisomerases regulate topological states of DNA and are divided into type I and type II enzymes. Type II topoisomerases make double stranded breaks in DNA and allow the passage of another duplex DNA across the break to achieve unknotting of entangled DNA. Topo II beta is one of two described isoforms that are likely products of a gene duplication event. TopoII beta is also described to be involved in chromosome condensation, chromatid separation, and the relief of supercoil stress.
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Gen-ID
- 7155
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NCBI Accession
- NP_001059
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UniProt
- Q02880
Target
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