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ERCC5 Antikörper (AA 650-700)

ERCC5 Reaktivität: Human WB, IP, IHC (fp) Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7453883
  • Target Alle ERCC5 Antikörper anzeigen
    ERCC5 (DNA Repair Protein Complementing XP-G Cells (ERCC5))
    Bindungsspezifität
    • 8
    • 8
    • 6
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 650-700
    Reaktivität
    • 44
    • 12
    • 11
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Human
    Wirt
    • 40
    • 4
    Kaninchen
    Klonalität
    • 41
    • 3
    Polyklonal
    Konjugat
    • 27
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser ERCC5 Antikörper ist unkonjugiert
    Applikation
    • 33
    • 19
    • 8
    • 6
    • 4
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))
    Verwendungszweck
    Rabbit anti-ERCC5/XPG Antibody, Affinity Purified
    Aufreinigung
    Affinity Purified
    Immunogen
    between AA 650 and 700
    Isotyp
    IgG
    Top Product
    Discover our top product ERCC5 Primärantikörper
  • Applikationshinweise

    IHC: 1:100 to 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

    IP: 2 - 10 μg/mg lysate

    WB: 1:2,000 - 1:10,000

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    200 μg/mL
    Buffer
    Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C
    Haltbarkeit
    12 months
  • Target
    ERCC5 (DNA Repair Protein Complementing XP-G Cells (ERCC5))
    Andere Bezeichnung
    ERCC5/XPG (ERCC5 Produkte)
    Synonyme
    COFS3 antikoerper, ERCM2 antikoerper, UVDR antikoerper, XPG antikoerper, XPGC antikoerper, cofs3 antikoerper, ercm2 antikoerper, uvdr antikoerper, xpg antikoerper, xpgc antikoerper, Xpg antikoerper, ERCC excision repair 5, endonuclease antikoerper, excision repair cross-complementation group 5 L homeolog antikoerper, excision repair cross-complementing rodent repair deficiency, complementation group 5 antikoerper, ERCC5 antikoerper, ercc5.L antikoerper, Ercc5 antikoerper
    Hintergrund
    Background: ERCC5 is a single-stranded DNA endonuclease involved in DNA excision repair. ERCC5 is an important component of the nucleotide excision repair (NER) pathway which is critical to the repair of DNA lesions caused by exposure to UV light. Defects in ERCC5 are the cause of xeroderma pigmentosum, an autosomal recessive disease characterized by a hypersensitivity to sunlight and a high predisposition to cancer on UV-exposed areas.
    Gen-ID
    2073
    NCBI Accession
    NP_000114
    UniProt
    P28715
    Pathways
    DNA Reparatur
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