ERCC5 Antikörper (AA 650-700)
Kurzübersicht für ERCC5 Antikörper (AA 650-700) (ABIN7453883)
Target
Alle ERCC5 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 650-700
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Verwendungszweck
- Rabbit anti-ERCC5/XPG Antibody, Affinity Purified
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Aufreinigung
- Affinity Purified
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Immunogen
- between AA 650 and 700
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Isotyp
- IgG
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Applikationshinweise
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IHC: 1:100 to 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
IP: 2 - 10 μg/mg lysate
WB: 1:2,000 - 1:10,000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 200 μg/mL
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Buffer
- Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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Haltbarkeit
- 12 months
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- ERCC5 (DNA Repair Protein Complementing XP-G Cells (ERCC5))
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Andere Bezeichnung
- ERCC5/XPG
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Hintergrund
- Background: ERCC5 is a single-stranded DNA endonuclease involved in DNA excision repair. ERCC5 is an important component of the nucleotide excision repair (NER) pathway which is critical to the repair of DNA lesions caused by exposure to UV light. Defects in ERCC5 are the cause of xeroderma pigmentosum, an autosomal recessive disease characterized by a hypersensitivity to sunlight and a high predisposition to cancer on UV-exposed areas.
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Gen-ID
- 2073
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NCBI Accession
- NP_000114
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UniProt
- P28715
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Pathways
- DNA Reparatur
Target
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