Prohibitin Antikörper (AA 222-272)

Produktnummer ABIN7453838

Der Kaninchen Polyklonal Anti-Prohibitin-Antikörper wurde für WB, IHC (fp) und IP validiert. Er ist geeignet, Prohibitin in Proben von Human zu detektieren.

Kurzübersicht für Prohibitin Antikörper (AA 222-272) (ABIN7453838)

Target: Prohibitin (PHB)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Prohibitin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp)), Immunoprecipitation (IP)

Produktdetails anti-Prohibitin Antikörper

Bindungsspezifität: AA 222-272

Verwendungszweck: Rabbit anti-Prohibitin Antibody, Affinity Purified

Homologie: Mouse,Rat,Bovine

Aufreinigung: Affinity Purified

Immunogen: between AA 222 and 272

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

IHC: 1:100 - 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: Not recommended

WB: 1:2,000 - 1:10,000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 200 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Haltbarkeit: 12 months

Details zu Prohibitin

Target: Prohibitin (PHB)

Andere Bezeichnung: Prohibitin

Hintergrund: Background: Prohibitin (PHB) has been identified as a tumor suppressor protein that can repress E2F-mediated transcription and arrest cell cycle progression. It has recently been shown to associate with members of the minichromosome maintenance complex such as MCM2, MCM5, and MCM7 and therefore is thought to impart its growth inhibitory effects via association with the replication machinery. Prohibitin is also implicated in regulating mitochondrial respiration and playing a role in aging.

Gen-ID: 5245

NCBI Accession: NP_002625

UniProt: P35232

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling