Prohibitin Antikörper

Produktnummer ABIN969353

Produktdetails anti-Prohibitin Antikörper

Target: Prohibitin (PHB)

Reaktivität: Human, Maus, Ratte, Affe

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Prohibitin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS), Immunocytochemistry (ICC)

Aufreinigung: purified

Immunogen: Purified recombinant fragment of human PHB expressed in E. coli.

Klon: 5H7

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000, ICC: 1:200 - 1:1000, FCM: 1:200 - 1:400

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: 4°C, -20°C for long term storage

Referenzen für anti-Prohibitin Antikörper (ABIN969353)

Shi, Li, Liu, Xu, Tang, Liang, Zhao, Yang: "Nuclear matrix protein, prohibitin, was down-regulated and translocated from nucleus to cytoplasm during the differentiation of osteosarcoma MG-63 cells induced by ginsenoside Rg1, cinnamic acid, and tanshinone IIA (RCT)." in: Journal of cellular biochemistry, Vol. 108, Issue 4, pp. 926-34, (2009) (PubMed).

Ande, Mishra: "Prohibitin interacts with phosphatidylinositol 3,4,5-triphosphate (PIP3) and modulates insulin signaling." in: Biochemical and biophysical research communications, Vol. 390, Issue 3, pp. 1023-8, (2009) (PubMed).

Details zu Prohibitin

Target: Prohibitin (PHB)

Andere Bezeichnung: PHB (PHB Produkte)

Synonyme: phb1 antikoerper, MGC75944 antikoerper, PHB antikoerper, Phb antikoerper, ACYPI000080 antikoerper, phb antikoerper, PHB1 antikoerper, Bap32 antikoerper, sr:nyz128 antikoerper, wu:fa18f07 antikoerper, wu:fb09f05 antikoerper, prohibitin1 antikoerper, xphb1 antikoerper, prohibitin antikoerper, prohibitin-2 antikoerper, prohibitin L homeolog antikoerper, PHB antikoerper, phb antikoerper, LOC484431 antikoerper, LOC5576054 antikoerper, Phb antikoerper, phb.L antikoerper

Hintergrund:

Description: Prohibitin is an evolutionarily conserved gene that is ubiquitously expressed. It is thought to be a negative regulator of cell proliferation and may be a tumor suppressor. Mutations in PHB have been linked to sporadic breast cancer. Prohibitin is expressed as two transcripts with varying lengths of 3' untranslated region. The longer transcript is present at higher levels in proliferating tissues and cells, suggesting that this longer 3' untranslated region may function as a trans-acting regulatory RNA.

Aliases: PHB1

Molekulargewicht: 30 kDa

Gen-ID: 5245

HGNC: 5245

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling