PRKDC Antikörper (AA 2100-2150)
Kurzübersicht für PRKDC Antikörper (AA 2100-2150) (ABIN7453820)
Target
Alle PRKDC Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 2100-2150
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Verwendungszweck
- Rabbit anti-DNA-PKcs Antibody, Affinity Purified
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Aufreinigung
- Affinity Purified
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Immunogen
- between AA 2100 and 2150
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Isotyp
- IgG
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Applikationshinweise
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IHC: 1:100 - 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
IP: ABIN7453820 is less efficient than ABIN7451557, ABIN7449674 or ABIN7451558.
WB: 1:1,000 - 1:10,000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 200 μg/mL
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Buffer
- Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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Haltbarkeit
- 12 months
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- PRKDC (Protein Kinase, DNA-Activated, Catalytic Polypeptide (PRKDC))
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Andere Bezeichnung
- DNA-PKcs
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Hintergrund
- Background: DNA-PKcs is the catalytic subunit of a DNA-dependent serine-threonine protein kinase (DNA-PK). DNA-PK is a heterotrimer comprised of DNA-PKcs and the Ku709/Ku86 dimer. DNA-PK is involved in DNA damage repair and V(D)J recombination. DNA-PK phosphorylates Artemis, a protein required for nonhomologous end-joining and is necessary for the loading of Artemis on damaged DNA.
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Gen-ID
- 5591
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NCBI Accession
- NP_008835
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UniProt
- P78527
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Pathways
- DNA Reparatur, Production of Molecular Mediator of Immune Response
Target
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