NLRP2 Antikörper (AA 704-754)

Produktnummer ABIN7453736

Produktdetails anti-NLRP2 Antikörper

Target: NLRP2 (NLR Family, Pyrin Domain Containing 2 (NLRP2))

Bindungsspezifität: AA 704-754

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NLRP2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Verwendungszweck: Rabbit anti-NBS1 Antibody, Affinity Purified

Homologie: Orangutan

Aufreinigung: Affinity Purified

Immunogen: between AA 704 and 754

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

IHC: 1:100 - 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 2 - 5 μg/mg lysate

WB: 1:2,000 - 1:10,000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 200 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Haltbarkeit: 12 months

Details zu NLRP2

Target: NLRP2 (NLR Family, Pyrin Domain Containing 2 (NLRP2))

Andere Bezeichnung: NBS1 (NLRP2 Produkte)

Synonyme: CLR19.9 antikoerper, NALP2 antikoerper, NBS1 antikoerper, PAN1 antikoerper, PYPAF2 antikoerper, NLRP2 antikoerper, E330007A02Rik antikoerper, Nalp2 antikoerper, NLR family pyrin domain containing 2 antikoerper, NACHT, LRR and PYD domains-containing protein 2 antikoerper, NLR family pyrin domain containing 7 antikoerper, NLR family, pyrin domain containing 2 antikoerper, NLRP2 antikoerper, LOC100301026 antikoerper, LOC100387349 antikoerper, NLRP7 antikoerper, Nlrp2 antikoerper

Hintergrund: Background: Mutations in NBS1 (Nijmegen Breakage Syndrome 1), also known as nibrin, are associated with the autosomal recessive syndrome, Nijmegen breakage syndrome, characterized by microcephaly, growth retardation, immunodeficiency, and cancer predisposition. At the cellular level, NBS1 is part of the MRE11/RAD50 double-strand break repair complex that is critical to the DNA damage response, DNA recombination, telomere integrity, and cell cycle checkpoint control.

Gen-ID: 4683

NCBI Accession: NP_002476

UniProt: O60934

Pathways: Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity, Inflammasome