NLRP2 Antikörper (AA 704-754)
Kurzübersicht für NLRP2 Antikörper (AA 704-754) (ABIN7453736)
Target
Alle NLRP2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 704-754
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Verwendungszweck
- Rabbit anti-NBS1 Antibody, Affinity Purified
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Homologie
- Orangutan
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Aufreinigung
- Affinity Purified
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Immunogen
- between AA 704 and 754
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Isotyp
- IgG
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Applikationshinweise
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IHC: 1:100 - 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
IP: 2 - 5 μg/mg lysate
WB: 1:2,000 - 1:10,000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 200 μg/mL
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Buffer
- Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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Haltbarkeit
- 12 months
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- NLRP2 (NLR Family, Pyrin Domain Containing 2 (NLRP2))
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Andere Bezeichnung
- NBS1
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Hintergrund
- Background: Mutations in NBS1 (Nijmegen Breakage Syndrome 1), also known as nibrin, are associated with the autosomal recessive syndrome, Nijmegen breakage syndrome, characterized by microcephaly, growth retardation, immunodeficiency, and cancer predisposition. At the cellular level, NBS1 is part of the MRE11/RAD50 double-strand break repair complex that is critical to the DNA damage response, DNA recombination, telomere integrity, and cell cycle checkpoint control.
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Gen-ID
- 4683
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NCBI Accession
- NP_002476
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UniProt
- O60934
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Pathways
- Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity, Inflammasome
Target
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