MBD2 Antikörper (AA 361-411)
Kurzübersicht für MBD2 Antikörper (AA 361-411) (ABIN7453726)
Target
Alle MBD2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 361-411
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Verwendungszweck
- Rabbit anti-MBD2 Antibody, Affinity Purified
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Aufreinigung
- Affinity Purified
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Immunogen
- between AA 361 and 411
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Isotyp
- IgG
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Applikationshinweise
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IHC: 1:100 - 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
IP: 2 - 5 μg/mg lysate
WB: 1:2,000 - 1:10,000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 200 μg/mL
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Buffer
- Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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Haltbarkeit
- 12 months
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- MBD2 (Methyl-CpG Binding Domain Protein 2 (MBD2))
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Andere Bezeichnung
- MBD2
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Hintergrund
- Background: MBD2 (methyl-CpG-binding domain protein 2) binds methylated CpG sites and represses gene transcription. DNA methylation is a common mechanism of gene silencing and is central to the developmental process. Methyl-CpG binding proteins (MBPs) have a high affinity for methylated DNA and are proposed to mediate gene silencing via the recruitment of histone deacetylases and other transcriptional repressors to chromatin.
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Gen-ID
- 8932
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NCBI Accession
- NP_003918
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UniProt
- Q9UBB5
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Pathways
- Chromatin Binding
Target
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