EYA3 Antikörper (AA 1-30)
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- Target Alle EYA3 Antikörper anzeigen
- EYA3 (Eyes Absent Homolog 3 (EYA3))
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Bindungsspezifität
- AA 1-30
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser EYA3 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))
- Verwendungszweck
- Rabbit anti-EYA3 Antibody, Affinity Purified
- Aufreinigung
- Affinity Purified
- Immunogen
- between AA 1 and 30
- Isotyp
- IgG
- Top Product
- Discover our top product EYA3 Primärantikörper
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- Applikationshinweise
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IHC: 1:100 - 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
IP: 2 - 5 μg/mg lysate
WB: 1:2,000 - 1:10,000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 200 μg/mL
- Buffer
- Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C
- Haltbarkeit
- 12 months
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- Target
- EYA3 (Eyes Absent Homolog 3 (EYA3))
- Andere Bezeichnung
- EYA3 (EYA3 Produkte)
- Hintergrund
- Background: EYA3 (eyes absent homolog 3) functions as a tyrosine phosphatase that specifically dephosphorylates 'Tyr-142' of histone H2AX (H2AXY142ph). EYA3 promotes efficient DNA repair by dephosphorylating H2AX and promoting the recruitment of DNA repair complexes containing MDC1. EYA3 coactivates SIX1. Together with SIX1 and DACH2 EYA3 seems to be involved in myogenesis. EYA3 may be involved in development of the eye [taken from the Universal Protein Resource (UniProt) Q99504].
- Gen-ID
- 2140
- NCBI Accession
- NP_001981
- UniProt
- Q99504
- Pathways
- Positive Regulation of Response to DNA Damage Stimulus
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