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EYA3 Antikörper (AA 1-30)

EYA3 Reaktivität: Human WB, IP, IHC (fp) Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7453703
  • Target Alle EYA3 Antikörper anzeigen
    EYA3 (Eyes Absent Homolog 3 (EYA3))
    Bindungsspezifität
    • 15
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 1-30
    Reaktivität
    • 31
    • 7
    • 6
    • 5
    • 5
    • 4
    • 4
    • 4
    • 4
    • 1
    • 1
    Human
    Wirt
    • 31
    Kaninchen
    Klonalität
    • 31
    Polyklonal
    Konjugat
    • 17
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser EYA3 Antikörper ist unkonjugiert
    Applikation
    • 28
    • 13
    • 13
    • 10
    • 8
    • 5
    • 5
    • 4
    • 3
    • 1
    Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))
    Verwendungszweck
    Rabbit anti-EYA3 Antibody, Affinity Purified
    Aufreinigung
    Affinity Purified
    Immunogen
    between AA 1 and 30
    Isotyp
    IgG
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    Discover our top product EYA3 Primärantikörper
  • Applikationshinweise

    IHC: 1:100 - 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

    IP: 2 - 5 μg/mg lysate

    WB: 1:2,000 - 1:10,000

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    200 μg/mL
    Buffer
    Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C
    Haltbarkeit
    12 months
  • Target
    EYA3 (Eyes Absent Homolog 3 (EYA3))
    Andere Bezeichnung
    EYA3 (EYA3 Produkte)
    Hintergrund
    Background: EYA3 (eyes absent homolog 3) functions as a tyrosine phosphatase that specifically dephosphorylates 'Tyr-142' of histone H2AX (H2AXY142ph). EYA3 promotes efficient DNA repair by dephosphorylating H2AX and promoting the recruitment of DNA repair complexes containing MDC1. EYA3 coactivates SIX1. Together with SIX1 and DACH2 EYA3 seems to be involved in myogenesis. EYA3 may be involved in development of the eye [taken from the Universal Protein Resource (UniProt) Q99504].
    Gen-ID
    2140
    NCBI Accession
    NP_001981
    UniProt
    Q99504
    Pathways
    Positive Regulation of Response to DNA Damage Stimulus
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