DERL1 Antikörper (AA 201-251)
Kurzübersicht für DERL1 Antikörper (AA 201-251) (ABIN7453690)
Target
Alle DERL1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 201-251
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Verwendungszweck
- Rabbit anti-Derlin-1 Antibody, Affinity Purified
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Homologie
- Bovine,Orangutan
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Aufreinigung
- Affinity Purified
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Immunogen
- between AA 201 and 251
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Isotyp
- IgG
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Applikationshinweise
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IHC: 1:100 - 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
IP: 2 - 5 μg/mg lysate
WB: 1:2,000 - 1:10,000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 200 μg/mL
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Buffer
- Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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Haltbarkeit
- 12 months
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- DERL1 (Der1-Like Domain Family, Member 1 (DERL1))
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Andere Bezeichnung
- Derlin-1
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Hintergrund
- Background: Derlin-1 (Degradation in endoplasmic reticulum protein 1) is a functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. Derlin-1 may act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome [taken from the Universal Protein Resource (UniProt) Q9BUN8].
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Gen-ID
- 79139
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NCBI Accession
- NP_077271
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UniProt
- Q9BUN8
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Pathways
- ER-Nucleus Signaling
Target
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