Cullin 3 Antikörper (AA 650-700)
Kurzübersicht für Cullin 3 Antikörper (AA 650-700) (ABIN7453602)
Target
Alle Cullin 3 (CUL3) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 650-700
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Verwendungszweck
- Rabbit anti-Cul3 Antibody, Affinity Purified
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Homologie
- Rat,X. laevis,X. tropicalis
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Aufreinigung
- Affinity Purified
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Immunogen
- between AA 650 and 700
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Isotyp
- IgG
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Applikationshinweise
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IHC: 1:100 - 1:1,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
IP: 2 - 5 μg/mg lysate
WB: 1:2,000 - 1:10,000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 200 μg/mL
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Buffer
- Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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Haltbarkeit
- 12 months
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- Cullin 3 (CUL3)
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Andere Bezeichnung
- Cul3
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Hintergrund
- Background: Cul3 is a member of the cullin group of proteins and functions as a scaffold to bring together ubiquitin E3 ligases, E2 conjugating enzyme, and substrate proteins to mediate the ubiquitination of substrate proteins. Cul3 and its associated ubiquitin ligase activity are essential for mitotic division and required for correct alignment of chromosomes and the completion of cytokinesis. Aurora B is a substrate of Cul3-based E3 ubiquitin ligase activity.
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Gen-ID
- 8452
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NCBI Accession
- NP_003581
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UniProt
- Q13618
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Pathways
- M Phase
Target
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