PKD2 Antikörper (C-Term)

Produktnummer ABIN7453565

Der Kaninchen-Polyklonal Anti-PKD2-Antikörper wurde für WB, IP und IHC (fp) validiert. Er ist geeignet zum Nachweis von PKD2 in Proben aus Human. }

Kurzübersicht für PKD2 Antikörper (C-Term) (ABIN7453565)

Target: PKD2 (Polycystic Kidney Disease 2 (Autosomal Dominant) (PKD2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PKD2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Produktdetails anti-PKD2 Antikörper

Bindungsspezifität: C-Term

Verwendungszweck: Rabbit anti-PKD2 Antibody, Affinity Purified

Aufreinigung: Affinity Purified

Immunogen: between AA 825 and C-term

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

IHC: 1:1,000 - 1:5,000. Epitope retrieval with Tris-EDTA pH 9.0 is recommended for FFPE tissue sections.

IP: 2 - 10 μg/mg lysate

WB: 1:200 - 1:10,000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Haltbarkeit: 12 months

Details zu PKD2

Target: PKD2 (Polycystic Kidney Disease 2 (Autosomal Dominant) (PKD2))

Andere Bezeichnung: PKD2

Hintergrund: Background: PKD2 is a member of the protein kinase D (PKD) family of serine/threonine protein kinases that belongs to a subfamily of the calcium-calmodulin kinase-like superfamily. PKD2 and its family members are activated by phorbol esters and diacylglycerol generated by PKC activation. PKD2 has been demonstrated to play a role in IL-2 promoter regulation as well as IL-8 production. PKD2 may also be involved in the regulation of trans-golgi network trafficking.

Gen-ID: 25865

NCBI Accession: NP_057541

UniProt: Q9BZL6

Pathways: cAMP Metabolic Process, Maintenance of Protein Location, Negative Regulation of Transporter Activity