PKD2 Antikörper (AA 240-410)

Produktnummer ABIN1682187

Produktdetails anti-PKD2 Antikörper

Target: PKD2 (Polycystic Kidney Disease 2 (Autosomal Dominant) (PKD2))

Bindungsspezifität: AA 240-410

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PKD2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: GMMSSNVYYY TRMMSQLFLD TPVSKTEKTN FKTLSSMEDF WKFTEGSLLD GLYWKMQPSN QTEADNRSFI FYENLLLGVP RIRQLRVRNG SCSIPQDLRD EIKECYDVYS VSSEDRAPFG PRNGTAWIYT SEKDLNGSSH WGIIATYSGA GYYLDLSRTR EETAAQVASL K

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 240-410 of human PKD2 (NP_000288.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu PKD2

Target: PKD2 (Polycystic Kidney Disease 2 (Autosomal Dominant) (PKD2))

Andere Bezeichnung: PKD2 (PKD2 Produkte)

Synonyme: APKD2 antikoerper, PC2 antikoerper, PKD4 antikoerper, Pc-2 antikoerper, TRPP2 antikoerper, C030034P18Rik antikoerper, RGD1559992 antikoerper, pkd2 antikoerper, trpp2 antikoerper, Cup antikoerper, PKD2L1 antikoerper, polycystin 2, transient receptor potential cation channel antikoerper, polycystic kidney disease 2 antikoerper, Polycystin-2 antikoerper, polycystin 2, transient receptor potential cation channel L homeolog antikoerper, PKD2 antikoerper, Pkd2 antikoerper, pkd-2 antikoerper, pkd2.L antikoerper, pkd2 antikoerper

Hintergrund: This gene encodes a member of the polycystin protein family. The encoded protein is a multi-pass membrane protein that functions as a calcium permeable cation channel, and is involved in calcium transport and calcium signaling in renal epithelial cells. This protein interacts with polycystin 1, and they may be partners in a common signaling cascade involved in tubular morphogenesis. Mutations in this gene are associated with autosomal dominant polycystic kidney disease type 2.,PKD2,APKD2,PC2,PKD4,Pc-2,TRPP2,Cancer,Signal Transduction,Cell Biology & Developmental Biology,Cell Cycle,Centrosome,Growth factor,EGF,Endocrine & Metabolism,Neuroscience,Calcium Signaling,PKD2

Molekulargewicht: 53 kDa/73 kDa/98 kDa/103 kDa/109 kDa

Gen-ID: 5311

UniProt: Q13563

Pathways: cAMP Metabolic Process, Maintenance of Protein Location, Negative Regulation of Transporter Activity