PKD2 Antikörper (AA 240-410)
Kurzübersicht für PKD2 Antikörper (AA 240-410) (ABIN1682187)
Target
Alle PKD2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 240-410
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Sequenz
- GMMSSNVYYY TRMMSQLFLD TPVSKTEKTN FKTLSSMEDF WKFTEGSLLD GLYWKMQPSN QTEADNRSFI FYENLLLGVP RIRQLRVRNG SCSIPQDLRD EIKECYDVYS VSSEDRAPFG PRNGTAWIYT SEKDLNGSSH WGIIATYSGA GYYLDLSRTR EETAAQVASL K
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Kreuzreaktivität
- Human, Maus, Ratte
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Produktmerkmale
- Polyclonal Antibodies
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Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 240-410 of human PKD2 (NP_000288.1).
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Isotyp
- IgG
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Applikationshinweise
- WB,1:500 - 1:1000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- PKD2 (Polycystic Kidney Disease 2 (Autosomal Dominant) (PKD2))
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Andere Bezeichnung
- PKD2
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Hintergrund
- This gene encodes a member of the polycystin protein family. The encoded protein is a multi-pass membrane protein that functions as a calcium permeable cation channel, and is involved in calcium transport and calcium signaling in renal epithelial cells. This protein interacts with polycystin 1, and they may be partners in a common signaling cascade involved in tubular morphogenesis. Mutations in this gene are associated with autosomal dominant polycystic kidney disease type 2.,PKD2,APKD2,PC2,PKD4,Pc-2,TRPP2,Cancer,Signal Transduction,Cell Biology & Developmental Biology,Cell Cycle,Centrosome,Growth factor,EGF,Endocrine & Metabolism,Neuroscience,Calcium Signaling,PKD2
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Molekulargewicht
- 53 kDa/73 kDa/98 kDa/103 kDa/109 kDa
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Gen-ID
- 5311
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UniProt
- Q13563
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Pathways
- cAMP Metabolic Process, Maintenance of Protein Location, Negative Regulation of Transporter Activity
Target
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