WDR77 Antikörper (AA 1-50)
Kurzübersicht für WDR77 Antikörper (AA 1-50) (ABIN7453513)
Target
Alle WDR77 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 1-50
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Verwendungszweck
- Rabbit anti-WDR77/MEP50 Antibody, Affinity Purified
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Homologie
- Bovine,Orangutan
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Aufreinigung
- Affinity Purified
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Immunogen
- between AA 1 and 50
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Isotyp
- IgG
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Applikationshinweise
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IHC: 1:1,000 - 1:5,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
IP: 2 - 5 μg/mg lysate
WB: Not recommended. Use rabbit anti-WDR77/MEP50 antibody A301-562A.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 1000 μg/mL
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Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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Haltbarkeit
- 12 months
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- WDR77 (WD Repeat Domain 77 (WDR77))
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Andere Bezeichnung
- WDR77/MEP50
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Hintergrund
- Background: WDR77/MEP50 is a component of the methylosome, a large protein arginine methyltransferase complex that modifies specific arginines to dimethylarginines in splicesomal Sm proteins. WDR77/MEP50 associates with the methyltransferase JBP1 (PRMT5) and is important for methylosome activity. WDR77/MEP50 has also been shown to associate with the polycomb group protein, SUZ12, and histone H2A. In this context, WDR77/MEP50 is proposed to function as an adaptor between PRMT5 and its substrate H2A to regulate transcription.
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Gen-ID
- 79084
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NCBI Accession
- NP_077007
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UniProt
- Q9BQA1
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Pathways
- Ribonucleoprotein Complex Subunit Organization
Target
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