HNF1A Antikörper (AA 550-600)
Kurzübersicht für HNF1A Antikörper (AA 550-600) (ABIN7453435)
Target
Alle HNF1A Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 550-600
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Verwendungszweck
- Rabbit anti-HNF1-alpha Antibody, Affinity Purified
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Aufreinigung
- Affinity Purified
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Immunogen
- Between AA 550 and 600
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Isotyp
- IgG
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Applikationshinweise
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IHC: 1:1,000 - 1:5,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
IP: 2 - 10 μg/mg lysate
WB: 1:2,000 - 1:10,000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 1000 μg/mL
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Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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Haltbarkeit
- 12 months
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- HNF1A (HNF1 Homeobox A (HNF1A))
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Andere Bezeichnung
- HNF1-alpha
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Hintergrund
- Background: Hepatocyte nuclear factor 1-alpha (HNF1-Alpha) is a transcription factor required for the expression of several liver-specific genes. HNF1-Alpha functions as a homodimer and binds to the inverted palindrome 5'-GTTAATNATTAAC-3'. Defects in the HNF1A gene are a cause of maturity onset diabetes of the young type 3 (MODY3) and also can result in the appearance of hepatic adenomas [taken from NCBI Entrez Gene (Gene ID: 6927)].
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Gen-ID
- 6927
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NCBI Accession
- NP_000536
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UniProt
- P20823
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Pathways
- Hormone Transport, Carbohydrate Homeostasis
Target
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