PRKDC Antikörper (AA 4078-4128)
Kurzübersicht für PRKDC Antikörper (AA 4078-4128) (ABIN7453431)
Target
Alle PRKDC Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
-
-
Bindungsspezifität
- AA 4078-4128
-
Verwendungszweck
- Goat anti-DNA-PKcs Antibody, Affinity Purified
-
Homologie
- Mouse
-
Aufreinigung
- Affinity Purified
-
Immunogen
- Between AA 4078 and 4128
-
Isotyp
- IgG
-
-
-
-
Applikationshinweise
-
IHC: 1:1,000 - 1:5,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
IP: 2 - 10 μg/mg lysate
WB: 1:2,000 - 1:10,000
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Konzentration
- 1000 μg/mL
-
Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
-
Konservierungsmittel
- Sodium azide
-
Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Lagerung
- 4 °C
-
Haltbarkeit
- 12 months
-
-
- PRKDC (Protein Kinase, DNA-Activated, Catalytic Polypeptide (PRKDC))
-
Andere Bezeichnung
- DNA-PKcs
-
Hintergrund
- Background: DNA-PKcs is the catalytic subunit of a DNA-dependent serine-threonine protein kinase (DNA-PK). DNA-PK is a heterotrimer comprised of DNA-PKcs and the Ku709/Ku86 dimer. DNA-PK is involved in DNA damage repair and V(D)J recombination. DNA-PK phosphorylates Artemis, a protein required for nonhomologous end-joining and is necessary for the loading of Artemis on damaged DNA.
-
Gen-ID
- 5591
-
NCBI Accession
- NP_008835
-
UniProt
- P78527
-
Pathways
- DNA Reparatur, Production of Molecular Mediator of Immune Response
Target
-