BRD4 Antikörper (AA 1312-1362)

Produktnummer ABIN7453424

Der Kaninchen Polyklonal Anti-BRD4-Antikörper wurde für WB, IP und IHC (fp) validiert. Er ist geeignet, BRD4 in Proben von Human und Maus zu detektieren.

Kurzübersicht für BRD4 Antikörper (AA 1312-1362) (ABIN7453424)

Target: BRD4 (Bromodomain Containing 4 (BRD4))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser BRD4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Produktdetails anti-BRD4 Antikörper

Bindungsspezifität: AA 1312-1362

Verwendungszweck: Rabbit anti-BRD4 Antibody, Affinity Purified

Aufreinigung: Affinity Purified

Immunogen: between AA 1312 and 1362

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

IHC: 1:1,000 - 1:5,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 2 - 10 μg/mg lysate

WB: 1:2,000 - 1:10,000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Haltbarkeit: 12 months

Details zu BRD4

Target: BRD4 (Bromodomain Containing 4 (BRD4))

Andere Bezeichnung: BRD4

Hintergrund: Background: Bromodomain-containing protein 4 (BRD4) contains 2 bromo-domains. Bromo-domains are found in chromatin-associating proteins and can interact specifically with acetylated lysine. BRD4 is described as a chromatin adaptor and has been shown to bind acetylated chromatin. It was originally identified as MCAP (mitotic chromosome associated protein) due to its association with mitotic chromosomes. BRD4 also associates with several transcription complexes such as the Mediator complexes and P-TEFb complexes and is considered to function as a transcriptional co-factor.

Gen-ID: 23476

NCBI Accession: NP_490597

UniProt: O60885

Pathways: Chromatin Binding, SARS-CoV-2 Protein Interaktom