DLD Antikörper (AA 459-509)

Produktnummer ABIN7453411

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch DLD in WB, IP und IHC (fp). Er zeigt eine Reaktivität gegenüber Human und Maus.

Kurzübersicht für DLD Antikörper (AA 459-509) (ABIN7453411)

Target: DLD (Dihydrolipoamide Dehydrogenase (DLD))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DLD Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Produktdetails anti-DLD Antikörper

Bindungsspezifität: AA 459-509

Verwendungszweck: Rabbit anti-DLD Antibody, Affinity Purified

Homologie: Dog,Orangutan

Aufreinigung: Affinity Purified

Immunogen: Between AA 459 and 509

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

IHC: 1:1,000 - 1:5,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 2 - 10 μg/mg lysate

WB: 1:1,000 - 1:5,000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Haltbarkeit: 12 months

Details zu DLD

Target: DLD (Dihydrolipoamide Dehydrogenase (DLD))

Andere Bezeichnung: DLD

Hintergrund: Background: Dihydrolipoamide dehydrogenase (DLD) is a member of the class-I pyridine nucleotide-disulfide oxidoreductase family. DLD has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. In homodimeric form, DLD functions as a dehydrogenase and is found in several multi-enzyme complexes that regulate energy metabolism. However, as a monomer, this protein can function as a protease. Mutations in this gene have been identified in patients with E3-deficient maple syrup urine disease and lipoamide dehydrogenase deficiency [taken from NCBI Entrez Gene (Gene ID: 1738)].

Gen-ID: 1738

NCBI Accession: NP_000099

UniProt: P09622

Pathways: Ribonucleoside Biosynthetic Process, Cell RedoxHomeostasis