CEP290 Antikörper (AA 2429-2479)

Produktnummer ABIN7453386

Produktdetails anti-CEP290 Antikörper

Target: CEP290 (Centrosomal Protein 290kDa (CEP290))

Bindungsspezifität: AA 2429-2479

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CEP290 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunoprecipitation (IP), Immunofluorescence (fixed cells) (IF/ICC)

Verwendungszweck: Rabbit anti-CEP290 Antibody, Affinity Purified

Aufreinigung: Affinity Purified

Immunogen: between AA 2429 and 2479

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

ICC-IF: 1:250 - 1:1,000. Formaldehyde fixation is recommended. Permeabilization with Triton-X 100 is recommended for formaldehyde-fixed cells.

IP: 2 - 5 μg/mg lysate

WB: 1:2,000 - 1:10,000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Haltbarkeit: 12 months

Details zu CEP290

Target: CEP290 (Centrosomal Protein 290kDa (CEP290))

Andere Bezeichnung: CEP290 (CEP290 Produkte)

Hintergrund: Background: Centrosomal protein 290 (CEP290) is a member of the nephrocystins, a family of proteins involved in renal cystic diseases. CEP290 and the nephrocystins appear to play a role in cilia and basal body function. Loss-of-function mutations in CEP290 result in Joubert syndrome and related disorders characterized by brain malformations, developmental delay, ataxia, irregular breathing, renal disease, and hepatic fibrosis.

Gen-ID: 80184

NCBI Accession: NP_079390

UniProt: O15078

Pathways: cAMP Metabolic Process, M Phase