Rekombinanter PDGFRA Antikörper (AA 24-525)
Kurzübersicht für Rekombinanter PDGFRA Antikörper (AA 24-525) (ABIN7453344)
Target
Alle PDGFRA Antikörper anzeigenAntikörpertyp
Reaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 24-525
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Verwendungszweck
- Rabbit anti-PDGFR alpha Recombinant Monoclonal Antibody [BLR128H]
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Immunogen
- residues 24-525 (ECD)
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Isotyp
- IgG
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Applikationshinweise
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IP: 6 μL/1 mg lysate
ICC: 1:100 to 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE cell sections.
WB: 01:01,00
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 1000 μg/mL
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Buffer
- Borate Buffered Saline (BBS) pH 8.2 with 0.09 % Sodium Azide, BSA-Free
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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Haltbarkeit
- 12 months
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- PDGFRA (Platelet Derived Growth Factor Receptor alpha (PDGFRA))
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Andere Bezeichnung
- PDGFR alpha
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Hintergrund
- Background: Platelet derived growth factor receptor alpha is a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both PDGFR alpha and beta polypeptides. PDGFR alpha plays a role in organ development, wound healing, and tumor progression [taken from NCBI Entrez Gene (Gene ID: 5156)].
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Gen-ID
- 5156
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NCBI Accession
- NP_006197
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UniProt
- P16234
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Pathways
- RTK Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Platelet-derived growth Factor Receptor Signaling
Target
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