PCGF2 Antikörper (AA 125-175)
Kurzübersicht für PCGF2 Antikörper (AA 125-175) (ABIN7453132)
Target
Alle PCGF2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 125-175
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Verwendungszweck
- Rabbit anti-Mel-18 Antibody, Affinity Purified
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Aufreinigung
- Affinity Purified
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Immunogen
- Between AA 125 and 175
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Isotyp
- IgG
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Applikationshinweise
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IP: Not recommended
WB: 1:2,000 - 1:10,000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 1000 μg/mL
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Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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Haltbarkeit
- 12 months
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- PCGF2 (Polycomb Group Ring Finger 2 (PCGF2))
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Andere Bezeichnung
- Mel-18
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Hintergrund
- Background: Mel18 is a transcriptional repressor and binds specifically to the DNA sequence 5'-GACTNGACT-3'. Mel-18 is a component of a polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. Mel-18 has tumor suppressor activity. Mel-18 plays a role in control of cell proliferation and/or neural cell development, and also plays a role in antero-posterior specification of the axial skeleton and negative regulation of the self-renewal activity of hematopoietic stem cells. [taken from the Universal Protein Resource (UniProt) P35227].
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Gen-ID
- 7703
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NCBI Accession
- NP_009075
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UniProt
- P35227
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Pathways
- Chromatin Binding
Target
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