LMTK2 Antikörper (AA 675-725)
Kurzübersicht für LMTK2 Antikörper (AA 675-725) (ABIN7453121)
Target
Alle LMTK2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 675-725
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Verwendungszweck
- Rabbit anti-LMTK2 Antibody, Affinity Purified
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Aufreinigung
- Affinity Purified
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Immunogen
- Between AA 675 and 725
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Isotyp
- IgG
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Applikationshinweise
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IP: Not recommended
WB: 1:2,000 - 1:10,000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 1000 μg/mL
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Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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Haltbarkeit
- 12 months
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- LMTK2 (Lemur tyrosine Kinase 2 (LMTK2))
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Andere Bezeichnung
- LMTK2
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Hintergrund
- Background: Lemur tyrosine kinase (LMTK2) belongs to the protein kinase superfamily and the protein tyrosine kinase family. It contains N-terminal transmembrane helices and a long C-terminal cytoplasmic tail with serine/threonine/tyrosine kinase activity. LMTK2 interacts with several other proteins, such as Inhibitor-2 (Inh2), protein phosphatase-1 (PP1C), p35, and myosin VI. It phosporylates other proteins, and is itself also phosporylated when interacting with cyclin-dependent kinase 5 (cdk5)/p35 complex. LMTK2 is involved in nerve growth factor (NGF)-TrkA signalling, and also plays a critical role in endosomal membrane trafficking. Mouse studies suggest an essential role of this protein in spermatogeness [taken from NCBI Entrez Gene (Gene ID: 22853)].
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Gen-ID
- 22853
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NCBI Accession
- NP_055731
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UniProt
- Q8IWU2
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Pathways
- RTK Signalweg, Neurotrophin Signalübertragung
Target
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