FNBP1 Antikörper (AA 567-617)
Kurzübersicht für FNBP1 Antikörper (AA 567-617) (ABIN7452760)
Target
Alle FNBP1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
-
-
Bindungsspezifität
- AA 567-617
-
Verwendungszweck
- Rabbit anti-FBP17 Antibody, Affinity Purified
-
Aufreinigung
- Affinity Purified
-
Immunogen
- between AA 567 and 617
-
Isotyp
- IgG
-
-
-
-
Applikationshinweise
-
IP: 5 - 15 μg/mg lysate
WB: 1:2,000 - 1:10,000
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Konzentration
- 1000 μg/mL
-
Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
-
Konservierungsmittel
- Sodium azide
-
Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Lagerung
- 4 °C
-
Haltbarkeit
- 12 months
-
-
- FNBP1 (Formin Binding Protein 1 (FNBP1))
-
Andere Bezeichnung
- FBP17
-
Hintergrund
- Background: FBP17 may act as a link between RND2 signaling and regulation of the actin cytoskeleton. FBP17 is required for the coordination of membrane tubulation and reorganization of the actin cytoskeleton during endocytosis. FBP17 binds to lipids such as phosphatidylinositol 4,5-bisphosphate and phosphatidylserine and promotes membrane invagination and the formation of tubules. It also enhances actin polymerization via the recruitment of WASL/N-WASP, which in turn activates the Arp2/3 complex. FBP17 may be required for the lysosomal retention of FASLG/FASL [taken from the Universal Protein Resource (UniProt) Q96RU3].
-
Gen-ID
- 23048
-
NCBI Accession
- NP_055848
-
UniProt
- Q96RU3
Target
-