DKC1 Antikörper (AA 340-390)
Kurzübersicht für DKC1 Antikörper (AA 340-390) (ABIN7452754)
Target
Alle DKC1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 340-390
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Verwendungszweck
- Rabbit anti-DKC1 Antibody, Affinity Purified
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Homologie
- Mouse,Rat,D. melanogaster,Chicken
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Aufreinigung
- Affinity Purified
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Immunogen
- between AA 340 and 390
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Isotyp
- IgG
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Applikationshinweise
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IP: 5 - 15 μg/mg lysate
WB: 1:2,000 - 1:10,000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 200 μg/mL
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Buffer
- Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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Haltbarkeit
- 12 months
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- DKC1 (Dyskeratosis Congenita 1, Dyskerin (DKC1))
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Andere Bezeichnung
- DKC1
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Hintergrund
- Background: Dyskeratosis congenita 1(DKC1) is also known as dyskerin. DKC1 is required for ribosome biogenesis and telomere maintenance. It is a probable catalytic subunit of H/ACA small nucleolar ribonucleoprotein (H/ACA snoRNP) complex, which catalyzes pseudouridylation of rRNA. DKC1 is also required for correct processing or intranuclear trafficking of TERC, the RNA component of the telomerase reverse transcriptase (TERT) holoenzyme. Defects in DKC1 are a cause of dyskeratosis congenita X-linked recessive (XDKC), a rare progressive bone marrow failure syndrome [taken from the Universal Protein Resource (UniProt) O60832].
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Gen-ID
- 1736
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NCBI Accession
- NP_001354
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UniProt
- O60832
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Pathways
- Telomere Maintenance
Target
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