DKC1 Antikörper
Kurzübersicht für DKC1 Antikörper (ABIN7266869)
Target
Alle DKC1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
-
-
Verwendungszweck
- DKC1 Rabbit mAb
-
Kreuzreaktivität
- Human, Maus, Ratte
-
Produktmerkmale
- Monoclonal Antibodies
-
Aufreinigung
- Affinity purification
-
Immunogen
- A synthesized peptide derived from human DKC1
-
Isotyp
- IgG
-
-
-
-
Applikationshinweise
- WB,1:500 - 1:2000,IHC,1:50 - 1:200
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Liquid
-
Buffer
- PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
-
Konservierungsmittel
- Sodium azide
-
Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Lagerung
- -20 °C
-
Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
-
-
- DKC1 (Dyskeratosis Congenita 1, Dyskerin (DKC1))
-
Andere Bezeichnung
- DKC1
-
Hintergrund
- This gene functions in two distinct complexes. It plays an active role in telomerase stabilization and maintenance, as well as recognition of snoRNAs containing H/ACA sequences which provides stability during biogenesis and assembly into H/ACA small nucleolar RNA ribonucleoproteins (snoRNPs). This gene is highly conserved and widely expressed, and may play additional roles in nucleo-cytoplasmic shuttling, DNA damage response, and cell adhesion. Mutations have been associated with X-linked dyskeratosis congenita. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014],CBF5, DKC, DKCX, NAP57, NOLA4, XAP101,Epigenetics & Nuclear Signaling,RNA Binding,DKC1
-
Molekulargewicht
- 58kDa
-
Gen-ID
- 1736
-
UniProt
- O60832
-
Pathways
- Telomere Maintenance
Target
-