BRCAA1 Antikörper (AA 450-500)

Produktnummer ABIN7452725

Der Kaninchen Polyklonal Anti-BRCAA1-Antikörper wurde für IP validiert. Er ist geeignet, BRCAA1 in Proben von Human zu detektieren.

Kurzübersicht für BRCAA1 Antikörper (AA 450-500) (ABIN7452725)

Target: BRCAA1 (ARID4B) (RBP1-like protein (ARID4B))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser BRCAA1 Antikörper ist unkonjugiert

Applikation: Immunoprecipitation (IP)

Produktdetails anti-BRCAA1 Antikörper

Bindungsspezifität: AA 450-500

Verwendungszweck: Rabbit anti-ARID4B Antibody, Affinity Purified

Aufreinigung: Affinity Purified

Immunogen: between AA 450 and 500

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

IP: 5 - 10 μg/mg lysate

WB: Not recommended. Use rabbit anti-ARID4B antibody ABIN7453522.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Haltbarkeit: 12 months

Details zu BRCAA1

Target: BRCAA1 (ARID4B) (RBP1-like protein (ARID4B))

Andere Bezeichnung: ARID4B

Hintergrund: Background: ARID4B (AT-rich interactive domain-containing protein 4B) is also known as RbBP1L1 (retinoblastoma binding protein 1-like 1) and is a retinoblastoma binding protein and member of the AT-rich interaction domain (ARID) family of proteins. In addition to the ARID DNA binding domain, ARID4B also contains a chromo domain and a TUDOR domain, indicating a function in chromatin organization and protein-protein interactions with methylated protein substrates. As a subunit of the SIN3A transcriptional co-repressor, ARID4B is implicated to be involved in chromatin remodeling and epigenetic modifications. ARID4B may play a role in the pathogenesis of breast cancer and other malignancies.

Gen-ID: 51742

NCBI Accession: NP_057458

UniProt: Q4LE39