BRCAA1 Antikörper (Internal Region)

Produktnummer ABIN7213842

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch BRCAA1 in WB und ELISA. Es zeigt Reaktivität gegenüber Proben von Human, Ratte und Maus.

Kurzübersicht für BRCAA1 Antikörper (Internal Region) (ABIN7213842)

Target: BRCAA1 (ARID4B) (RBP1-like protein (ARID4B))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser BRCAA1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-BRCAA1 Antikörper

Bindungsspezifität: Internal Region

Verwendungszweck: Rabbit Anti-BRCAA1 Polyclonal Antibody

Spezifität: BRCAA1 Polyclonal Antibody detects endogenous levels of BRCAA1 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human BRCAA1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,ELISA 1:10000,Not yet tested in other applications.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu BRCAA1

Target: BRCAA1 (ARID4B) (RBP1-like protein (ARID4B))

Andere Bezeichnung: BRCAA1

Hintergrund: ARID4B, BRCAA1, RBBP1L1, RBP1L1, SAP180, AT-rich interactive domain-containing protein 4B, ARID domain-containing protein 4B, 180 kDa Sin3-associated polypeptide, Sin3-associated polypeptide p180, Breast cancer-associated antigen BRCAA1, HiARID4B encodes a protein with sequence similarity to retinoblastoma-binding protein-1. The encoded protein (AT-rich interaction domain 4B) is a subunit of the histone deacetylase-dependant SIN3A transcriptional corepressor complex, which functions in diverse cellular processes including proliferation, differentiation, apoptosis, oncogenesis, and cell fate determination. The gene product is recognized by IgG antibody isolated from a breast cancer patient and appears to be a molecular marker associated with a broad range of human malignancies. Alternate transcriptional splice variants encoding different isoforms have been characterized.

Molekulargewicht: 148kD

Gen-ID: 51742

UniProt: Q4LE39