Rekombinanter FOXO3 Antikörper (AA 450-500)
Kurzübersicht für Rekombinanter FOXO3 Antikörper (AA 450-500) (ABIN7452580)
Target
Alle FOXO3 Antikörper anzeigenAntikörpertyp
Reaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 450-500
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Verwendungszweck
- Rabbit anti-FOXO3a Recombinant Monoclonal Antibody [BLR140H]
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Immunogen
- between AA 450 and 500
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Isotyp
- IgG
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Applikationshinweise
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IP: 20 μL/1 mg lysate
WB: 01:01,00
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 40 μg/mL
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Buffer
- Borate Buffered Saline (BBS) pH 8.2 with 0.1 % BSA and 0.09 % Sodium Azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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Haltbarkeit
- 12 months
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- FOXO3 (Forkhead Box O3 (FOXO3))
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Andere Bezeichnung
- FOXO3a
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Hintergrund
- Background: Forkhead box protein 03A (FOXO3a) belongs to a large family of Forkhead proteins that possesses a winged-helix DNA-binding domain called Forkhead box (FOX). FOXO3a is a transcription factor that functions to induce apoptosis in the absence of survival factors and in response to oxidative stress. Under conditions of oxidative stress FOXO3a is acetylated and localized to the nucleus where it may act as a transcriptional repressor.
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Gen-ID
- 2309
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NCBI Accession
- NP_001446
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UniProt
- O43524
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Pathways
- Zellzyklus, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Carbohydrate Homeostasis
Target
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