UBR1 Antikörper (AA 225-275)
Kurzübersicht für UBR1 Antikörper (AA 225-275) (ABIN7452547)
Target
Alle UBR1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
-
-
Bindungsspezifität
- AA 225-275
-
Verwendungszweck
- Rabbit anti-UBR1 Antibody, Affinity Purified
-
Aufreinigung
- Affinity Purified
-
Immunogen
- between AA 225 and 275
-
Isotyp
- IgG
-
-
-
-
Applikationshinweise
-
IP: 2 - 5 μg/mg lysate
WB: Not recommended
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Konzentration
- 1000 μg/mL
-
Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
-
Konservierungsmittel
- Sodium azide
-
Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Lagerung
- 4 °C
-
Haltbarkeit
- 12 months
-
-
- UBR1 (Ubiquitin Protein Ligase E3 Component N-Recognin 1 (UBR1))
-
Andere Bezeichnung
- UBR1
-
Hintergrund
- Background: UBR1 is an E3 ubiquitin-protein ligase that is a component of the N-end rule pathway. UBR1 recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation. UBR1 may be involved in pancreatic homeostasis. UBR1 binds leucine and is a negative regulator of the leucine-mTOR signaling pathway, thereby controlling cell growth [taken from the Universal Protein Resource (UniProt) Q8IWV7].
-
Gen-ID
- 197131
-
NCBI Accession
- NP_777576
-
UniProt
- Q8IWV7
Target
-