KIDINS220 Antikörper (AA 1721-1771)
Kurzübersicht für KIDINS220 Antikörper (AA 1721-1771) (ABIN7452488)
Target
Alle KIDINS220 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 1721-1771
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Verwendungszweck
- Rabbit anti-ARMS Antibody, Affinity Purified
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Homologie
- Rat
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Aufreinigung
- Affinity Purified
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Immunogen
- between AA 1721 and 1771
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Isotyp
- IgG
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Applikationshinweise
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IP: 2 - 5 μg/mg lysate
WB: Not recommended
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 1000 μg/mL
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Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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Haltbarkeit
- 12 months
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- KIDINS220 (Kinase D-Interacting Substrate, 220kDa (KIDINS220))
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Andere Bezeichnung
- ARMS
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Hintergrund
- Background: Ankyrin repeat-rich membrane-spanning protein (ARMS) is also known as Kinase D-interacting substrate of 220 kDa (KIDINS220). ARMS Promotes prolonged MAP-kinase signaling by neurotrophins through activation of a Rap1-dependent mechanism. Arms may play an important role in regulating postsynaptic signal transduction through the syntrophin-mediated localization of receptor tyrosine kinases such as EPHA4. ARMS may play a role in neurotrophin- and ephrin-mediated neuronal outgrowth and in axon guidance during neural development and in neuronal regeneration. ARMS has also been shown to modulate stress-induced apoptosis of melanoma cells via regulation of the MEK/ERK signaling pathway [taken from the Universal Protein Resource (UniProt) Q9ULH0].
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Gen-ID
- 57498
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NCBI Accession
- NP_065789
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UniProt
- Q9ULH0
Target
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