SUFUH Antikörper (AA 325-375)
Kurzübersicht für SUFUH Antikörper (AA 325-375) (ABIN7452445)
Target
Alle SUFUH Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 325-375
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Verwendungszweck
- Rabbit anti-SuFu Antibody, Affinity Purified
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Aufreinigung
- Affinity Purified
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Immunogen
- between AA 325 and 375
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Isotyp
- IgG
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Applikationshinweise
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IP: 2 - 5 μg/mg lysate
WB: Not recommended. Use rabbit anti-SuFu antibody ABIN7452074.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 1000 μg/mL
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Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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Haltbarkeit
- 12 months
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- SUFUH (Suppressor of Fused Homolog (SUFUH))
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Andere Bezeichnung
- SuFu
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Hintergrund
- Background: Suppressor of fused (SuFu) is a negative regulator of the hedgehog and beta-catenin signaling pathway. It down-regulates GLI1-mediated transactivation of target genes and is part of a corepressor complex that acts on DNA-bound GLI1. SuFu may also act by linking GLI1 to BTRC and thereby targeting GLI1 to degradation by the proteasome. Additionally, SuFu sequesters GLI1, GLI2 and GLI3 in the cytoplasm, this effect is overcome by binding of STK36 to both SUFU and a GLI protein [taken from the Universal Protein Resource (UniProt) Q9UMX1].
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Gen-ID
- 51684
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NCBI Accession
- NP_057253
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UniProt
- Q9UMX1
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Pathways
- Hedgehog Signalweg, Tube Formation, Maintenance of Protein Location
Target
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